UNIVERSAL - ZeroR AC Refrigerant is a hydrocarbon that safely bonds with chemicals like R134a, R1234YF and R12. We can only advertise this product to be used in R134a systems due to EPA regulations in the USA on both R12 and R1234YF systems. EPA also prohibits mixing refrigerant types. See the description for all legal disclaimers. EASY - This product installs just as easily as any R134a products. Cans even have R134a threads and the majority of R134a can taps will work for these cans. 6oz CANS - Refrigerants are compressed gasses and are measured by weight, not by liquid volume such as water. All gasses compress differently and produce a different weight. ZeroR AC Refrigerant is low weight compared to R134a, but its performance is equal to 16oz of R134a. ECO FRIENDLY & USA MADE ? ZeroR AC Refrigerant is a 100% Natural gas unlike R134a, R1234yf and R12. This product is Made in the USA. SAFE ? ZeroR AC Refrigerant has a class 2.1 flammability rating just like the new R1234YF which is now used in 100% of newly manufactured vehicles. Under normal operating conditions this product presents no danger to its users when handled properly and used in systems approved for flammable refrigerants. LEGAL - USA EPA REGULATIONS: ZeroR AC Refrigerant should only be used in R134a systems. The mixing of any refrigerant types. This product is not being advertised for use in R12 or R1234YF system types. FLAMMABILITY: This product is flammable and should be handled and stored in a safe environment suitable for flammable products. We recommend only using this product in systems designed for flammable refrigerants. See product label for additional safety information.