Feature

●Concentration of urine prior to electrophoresis for diagnosis of multiple myeloma and amyloidosis
●Concentrate spinal fluid prior to electrophoresis for diagnosis of meningitis & multiple sclerosis
●Free drug & hormone (T3/T4) analysis. Process samples in 30 minutes vs 17 hours for equil dialysis.
●Protein removal from serum & cell / tissue lysates
●Exchange buffers for proteomic peptide samples


Description

Vivaspin 20 Centrifugal Ultra Filter (50,000 MWCO, PES Membrane, 12 per pack)

The Vivaspin® 20ml centrifugal concentrators have been developed to offer increased volume flexibility and performance.

Vivaspin® 20 handles up to 20ml in swing bucket centrifuges 14ml in 25° fixed angle rotors accepting 50ml centrifuge tubes. Featuring twin vertical membranes for unparalleled filtration speeds and 100X plus concentrations. Remaining volume is easy to read off the printed scale on the side of the concentrator and the modified dead stop pocket further simplifies direct pipette recovery of the final concentrate.

Process Flexibility
Vivaspin® 20 is available with unique accessories and operating methods that are designed to provide more process flexibility and further time saving.

One Step Desalting
In this procedure following concentration, a diafiltration cup is filled with buffer and then spun one time to achieve 98% salt removal. This compares to the need for two spins to achieve the same result with the traditional refill and re-spin procedure.

The improved performance is due to the constant washing action of the buffer solution in the accessory cup as it replaces solvent and salts as they pass through the ultrafiltration membrane.

Gas Pressure Filtration
When an appropriate centrifuge is unavailable, or for single sample processing, Vivaspin® 20 can be filled with up to 15ml and then pressurised for bench top concentration. For even faster processing, Gas pressure can be combined with centrifugal force. "Pressure-fugation" is particularly suitable for difficult or viscous samples such as serum, or when using a low process temperature which reduces filtration speed, and generally when minimum process time is essential.